Basic Physiology of Life Style Disease ?

According to Dr. Otto Heinrich Warburg 1931 Nobel Prize Winner, many diseases thrive in an acidic environment
Biochemist Otto Heinrich Warburg, one of the twentieth century’s leading cell biologists, discovered that the root cause of cancer is too much acidity in the body, meaning that the pH, potential hydrogen, in the body is below the normal level of 7.365, which constitutes an “acidic “state. Warburg investigated the metabolism of tumors and the respiration of cells and discovered that cancer cells maintain and thrive in a lower pH, as low as 6.0, due to lactic acid production and elevated CO2.He firmly believed that there was a direct relationship between pH and oxygen. Higher pH, which is Alkaline, means higher concentration of oxygen molecules, while lower pH, which is acidic, means lower concentrations of oxygen…the same oxygen that is needed to maintain healthy cells. In 1931 he was awarded the Nobel Prize in Medicine for this important discovery. Dr. Warburg was director of the Kaiser Wilhelm Institute (now Max Planck Institute) for cell physiology at Berlin. He investigated the metabolism of tumors and the respiration of cells, particularly cancer cells. Below are some direct quotes by Dr. Warburg during medical lectures where he was the keynote speaker:
“Cancerous tissues are acidic, whereas healthy tissues are alkaline. Water splits into H+ and OH-ions, if there is an excess of H+, it is acidic; if there is an excess of OH-ions, then it is alkaline.”

The Metabolism of Tumors

Warburg demonstrated that all forms of cancer are characterized by two basic conditions: acidosis and hypoxia (lack of oxygen). “Lack of oxygen and acidosis are two sides of the same coin: where you have one, you have the other.” All normal cells have an absolute requirement for oxygen, but cancer cells can live without oxygen -a rule without exception. “Deprive a cell 35% of its oxygen for 48 hours and it may become cancerous.”Dr. Warburg has made it clear that the root cause of cancer is oxygen deficiency, which creates an acidic state in the human body. Dr. Warburg also discovered that cancer cells are anaerobic (do not breathe oxygen) and cannot survive in the presence of high levels of oxygen, as found in an alkaline state.


As with exercise, a mild to moderate amount of emotional stress produces only a slight increase in free radicals. Severe emotional stress, however, causes the number of free radicals to rise significantly, creating oxidative stress. Have you ever noticed that when you are under a lot of pressure you frequently become sick? How many times have you known a close friend or family member who has been under tremendous stress for a prolonged period of time only to discover he has developed cancer or had a first heart attack?
The root cause of disease is stress. Stress is defined as a straining force, an imbalance of forces. Stress is a form of opposition that stimulates adaptation, growth and development in any life form exposed to it. Stress is only “bad” when it is excessive, unbalanced and unchecked.shutterstock_227750149
The stress of pressure turns graphite into diamonds. The stress of sunlight is captured by chlorophyll in plants and converted into an energy form (glucose) that feeds the growth of the plant. The stress of the birthing process gives rise to new life. It was stress that formed the Grand Canyon, Niagara Falls and the Hawaiian Islands. Stress on muscles force them to grow in response to the opposition they encounter. Stress is a necessary stimulus for life. It is a catalyst for beauty and growth. However, when stress exceeds our limits to contain and manage it, disharmony and imbalance result.
In living organisms, unchecked, unbalanced stress is the stimulus for disease. I will present three of the most common types that I have seen and managed as a physician –
  1. Oxidative Stress
  2. Acidic Stress
  3. Hydration Stress.

Before that we have to Understand Free Radical

The War Within.
SIT BACK, CLOSE YOUR EYES FOR A MOMENT, AND FOCUS ON YOUR breathing. Relax your shoulders and breathe in as deeply as you can, and then slowly release the air from your lungs. Do this several times. Breathe as if you are inflating your whole body, clear down to your toes. Pause and then slowly exhale. Feels great, doesn’t it? The air that enters our lungs brings life. And as we quicken our breathing through aerobic exercise or running, we feel invigorated and may even experience a feeling of euphoria.
Being a doctor, I like to imagine what is happening inside my body at a cellular level as oxygen enters through my nose and travels to my lungs. Life is an intricately woven miracle, evident in every breath. I fill my lungs with fresh air rich with oxygen. The molecules of oxygen then pass through the thin walls of the alveoli in the lungs into the blood that is passing by. Here it attaches itself to the hemoglobin in my blood, and my beating heart pumps this newly oxygenated blood back out to all parts of my body. The hemoglobin then releases the oxygen so it can enter the cells of my body, where it gives energy and life itself.
Within every cell in the body is a furnace called the mitochondria. Imagine yourself in front of a crackling, warm fire. It burns safely and quietly most of the time. But on occasion, out flies a cinder that lands on your carpet, burning a little hole in it. One cinder by itself does not pose much of a threat; but if this sparking and popping continues month after month, year after year, you will end up with a pretty ragged carpet in front of your fireplace.
Similarly, this microscopic organism, the mitochondria, within the cell reduces oxygen by the transfer of electrons to create energy into the form of ATP, and produces a by­product of water. This process goes on without a hitch at least 98 percent of the time. But the full complement of four electrons needed to reduce oxygen to water does not always happen as planned and a “free radical” is produced.
A free radical is an oxygen containing molecule that has one or more unpaired electrons, making it highly reactive with other molecules.
However, free radicals can chemically interact with cell components such as DNA, protein or lipid and steal their electrons in order to become stabilized.
This, in turn, destabilizes the cellcomponent molecules which then seek and steal an electron from another molecule, therefore triggering a large chain of free radical reactions.

Oxidative Stress

Oxidative stress is the root cause of chronic disease. It is also believed to be responsible for the aging process. In simple terms oxidative stress is the chemical process of stealing electrons. It is a natural and predictable part of day-to-day cellular activity.3 ed page What is Oxidative Stress
When the oxygen molecule loses an electron, it becomes a free radical and begins to search for any molecule that might have an extra electron. Oxidation occurs when an electron is taken from a molecule by oxygen. Oxidation is how our bodies age, resulting in wrinkles. degeneration of organs, bones, muscles, tendons and cellular membranes.

How Bad is Oxidative Stress?


Acidic Stress

Acidic Stress is a precursor to oxidative stress. By definition, acidic stress is the result of chronic acid exposure, primarily from diets high in sugars, animal protein (especially red meat and dairy products), emotional stress, physical stress (via lactic acid buildup) or elimination problems such as kidney failure.stress-and-cancer-hormones
The body goes to extreme measures to maintain a slightly alkaline pH in most tissues. For example, blood, the lifeline of the body, has an optimal pH of 7.35 – 7.45. Three primary buffering systems exist to help maintain this narrow pH window, underscoring the critical nature of pH in optimal physiology. The most powerful and rapid buffering system is the lungs. The faster we breathe the more acidic carbon dioxide we exhale, taking us back towards neutrality. Heavy breathing with exercise is a prime example of this quick and efficient mechanism of buffering the blood.  The kidneys are the second major buffering system. Urine with a mean pH of 6.0 is nearly 15 times as acidic as blood because its role is to eliminate much of the acidic buildup that occurs within the body as a result of metabolism and exercise. When blood becomes overly acidic, the kidneys can reabsorb alkaline bicarbonate and excrete acidic hydrogen ions. This is a slower process that can take hours to days to fully buffer the blood but this system can do so with extreme precision, especially when the lungs are damaged because of health issues like chronic obstructive pulmonary disease (COPD).

Hydration Stress

We are more then 75% water, one big biochemical reaction. The aging process seems to be associated with a relative loss of hydration. The elderly are believed to be only 65% water, while infants are very hydrated (75-80%). Due to the polar nature of water, it is the ideal solvent. We can weeks without food but only days without water. We are much more likely to be dehydrated than hungry.40-body-water

What are antioxidants?

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